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C.
LECTURE TIMES AND VENUE:
Lectures will be held in ET Room 107, Tuesdays and Thursdays, 9.30 -10.45
p.m. You are responsible for all announcements, assignments, handouts,
etc. even if you are late or absent from class.
Required Text:
Principles of Ecotoxiology:
by
Walker, C. H., and Hopkin, S. P., and Sibly, R. M.
Edition: 3rd ed. Publisher:
CRC Press Date Published: 2005
ISBN-13:
9780849336355 ISBN:
084933635X
Recommended Text:Aquatic
Toxicology: Molecular, Biochemical, and Cellular Perspectives:
Donald C. Malins and
Gary K. Ostrander. 1993,
Lewis Publishers, Inc.; 520 pp., ISBN: 0-87371-545-4 Fundamentals of Aquatic Toxicology. Effects,
Environmental Fate and Risk Assessment. 2nd Ed. Ed G.
Rand. Taylor and Francis. Philadelphia,
London. ISBN 1-56032-091-5
Quantitative Chemical Analysis. 7th Edition. Harris, D.C. W.H. Freeman and Company, New York.
2006, 928 pp., ISBN : 0716776944, QD101.2.H37
Exploring Chemical Analysis. 3rd Edition. Harris, D.C. W.H. Freeman and Company, New York.
2005, 610 pp. ISBN 0716705710
. QD75.2.H368
LECTURE OUTLINE: A general lecture outline is given below
describing some of the topics that will be discussed in lecture.
Depending upon the depth and breadth of the subject matter, various topics
may cover more than an individual lecture period. Consequently, no
attempt has been made to allocate proposed dates.
| Lecture |
Topic |
| 1 |
Outline of Course Syllabus & Introduction to Aquatic
Toxicology. |
| 2 |
Major Classes of Pollutants (Inorganics, Organics, Radiation
etc) |
| 3 |
Routes by Which Pollutants Enter the Aquatic Ecosystems.
A case study of the Colorado Lagoon, Long Beach. (field trip
to collect samples and deploy caged mussels) |
| 4 |
Direct Chemical methods
for the identification, quantification and speciation of inorganic
pollutants I |
| 5 |
Direct Chemical methods
for the identification, quantification and speciation of
inorganic/organic
pollutants II |
| 6 |
Direct Chemical methods
for the identification, quantification and speciation of organic
pollutants III
|
| 7 |
Determination of Toxicity:
Toxicity
Testing. Trials and Tribulations |
| 8 |
Toxicity Assessment: End
points in Toxicity (Acute versus Chronic; Lethal versus physiological) |
| 9 |
Behavioral responses to toxicants |
| 10 |
Physiological responses to toxicants |
| 11 |
Biochemical responses to toxicants |
| 12 |
Cellular and Molecular responses to toxicants |
| 13 |
Biomarkers of Xenobiotic Stress (organismal, cell/tissue,
subcellular) |
| 14 |
Biomarkers of Xenobiotic Stress (Alarm parameters, Toxicity
stress/strain parameters/ Finger print parameters) |
| 15 |
Molecular Mechanisms of interaction of Inorganics
(Metallothioneins) |
| 16 |
Molecular Mechanisms of interaction of Organics
(Cytochrome
P-450) |
| 17 |
Recombinant reporter assays for Toxicological Assessment |
| 18 |
Case Studies in Toxicology (Cytochrome P-450 induction
and Endocrine Disruption by TBT). |
| 19-24
|
STUDENT PRESENTATIONS
I - IV
|
| Various |
Guest Lecturers (D. Schlenk, M. Ronis, S.
Bay, R. Gossett) |
| 25 |
FINAL
EXAM: Tuesday, May 20th, ET Room 107
10.15 a.m. - 12.15 p.m. |
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