The facility is equipped with three fume hoods and two Barnstead Nanopure™ reagent water systems for the production of 18 megohm ultra-pure water free of trace metal contamination and pyrogens.  Other equipment in this laboratory includes 2 dual-gradient HPLC’s (Two Beckman™ system 32 Karat 126 solvent delivery modules with two168 Diode Array UV/VIS detectors) and a quaternary Waters™ HPLC with a 484MS tunable detector. 

The laboratory is also equipped with 2 D SDS-PAGE and TLC,  various homogenizers, a UV-visible spectrophotometer, a lyophilizer, low and medium speed centrifuges and auxiliary equipment such as pH meters and balances. Two Lab-Line environmental chambers with full sub-ambient temperature control are available for maintaining animals and cells in radioactive media.  

The ICP-MS room houses a HP™ 4500 ICP-MS and a Perkin Elmer™ 6100 DRC, dual quadrupole ICP-MS with hydride generation facility and a flow injection analysis system.  The room was designed specifically to meet class 1000 specifications and to be metal free.  It covers an area of 450 sq.ft which is divided into 3 functional areas: an air locked vestibule; the instrument area; and the wet laboratory. 

 All flooring is composed of a hermetically seam-sealed, chemically resistant, polymer. The wet preparation section has four Teflon coated benches that are provided ultrapure from a Barnes water system that receives house water that has been purified by reverse osmosis.  A quartz still, located in a Teflon-lined chemical hood, is available for redistillation of mineral acids. An additional laminar flow hood is available for sample preparation.  The second bench houses 6 mineral acid baths for cleaning and decontaminating glassware.  

The final two benches are mobile and are designated for sample preparation and transportation to the instrument.  The third laboratory is dedicated to organic two HP-VG Trio GC-MS’s. Ancillary equipment for the rotor evaporation and microwave digestion of samples are also located in the fume hood in this laboratory.  A heavy duty, industrial type, -80^oC freezers with liquid CO₂ backup and a chest style –20^oC refrigerator together with 3 conventional refrigerators are located in this laboratory for sample storage. 

The fourth laboratory is used primarily for radioisotope studies and houses a Beckman™ liquid scintillation counter and a LKB CompuGamma™ counter with the ability to deconvolute 4 isotopic channels.  Other equipment available outside of the laboratory include a Beckman ultracentrifuge, a cell culture facility with a sub-ambient  CO₂, humidity and temperature controlled Forma Scientific incubator inverted scopes, laminar-flow hoods. 

Other equipment available for use include a Beckman DU-640B UV/Vis Spectrophotometer, Savant Speed vac System with cryovacuum system, Pharmacia FPLC Protein Separation System, Northern Blotting, and PCR thermo-recyclers and automated DNA sequencing systems. 

Other equipment associated with the molecular toxicology facility include a JEOL™ 1200EXII Transmission electron microscope with a CCD camera and an AMRAY™ 1830T SEM with full analytical capability including a backscatter detector, cathode-illuminescence and EDX and WDX detectors.