Chem 320A. Organic Chemistry (3 Units) Fall, Spring
Prerequisites: Chemistry 111B with a grade of C or better.  Chem 251 is recommended. The first semester of a two semester sequence (Chem 320A and 320B).  This sequence meets the requirements for medical and dental schools.  Emphasis is upon the application of modern principles of structure, reactivity, methods of synthesis, physical properties and spectroscopy.  Not open to students in Chem 321A.  (Lecture 3 hrs., discussion 1 hr.)

Chem 320B.  Organic Chemistry (5)              FALL 1999
Prerequisites: Chem 320A with a grade of C or better.  The second semester of a two semester sequence (Chem 320A and 320B).   A continuation of the study of organic chemistry including the chemistry of compounds containing more than one functional group, bioorganic molecules and special topics.  Not open to students with credit in Chem 321 B or 322.  (Lecture 3 hrs., laboratory 6 hrs.)  A course fee may be required.

Chem 327.  Organic Chemistry (3)
Prerequisites: Chem 111A with a grade of C or better; Chem 111B is recommended.  Chem 201A or Chem 202 may not substitute for Chem 111A.  Lecture course in the chemistry of carbon compounds.  Not applicable to a degree in chemistry.  (Lecture 3 hrs.)

Chem 421/521. Physical Organic Chemistry (3 Units) Fall
Prerequisites: Chemistry 320B with a grade of C or better or pass the organic entrance exam; 371B or 377B (may be taken concurrently). Theoretical interpretation of the chemical and physical properties of organic compounds including the following: mathematical derivations of rate equations from experimental results, calculations of reaction rate constants from experimental data, quantitative comparison of the  reactivates of organic compounds, mathematical correlations of structure and properties. Practice in solving problems relating reaction mechanisms to the factors derived above. (Lecture 3 hours.)

Chem 522. Special Topics in Organic Chemistry (3 Units) Fall, Spring
Prerequisite: Chemistry 421 or 521 or consent of instructor. Areas of current interest in
organic chemistry. Normally two of the following topics are treated. May be repeated with
different topics to a maximum of six units.

• Natural Products: Structure, biological activity, biogenesis and synthesis of selected naturally occurring compounds.
• Organic Synthesis: Modern synthetic reactions as demonstrated in recent syntheses of molecules of biological or theoretical interest.
• Organophosphorus Chemistry: Nomenclature, synthesis and reactivity of phosphorus-containing organic compounds. Emphasis is placed upon mechanisms of reactions of such compounds. Some discussion of the biochemistry of organophosphorus compounds will be given.
• Photochemistry: The effects of light absorption by organic compounds. Involves a study of the types and mechanisms of reactions, energy transfer, fluorescence and phosphorescence.
• Kinetics and Mechanism: A survey of methods of elucidation of reaction mechanisms. Theory and application of kinetics, isotope effects, acidity functions. Catalysis and linear free energy relationships may be included as related to molecular rearrangements, hydrolyses, hydration reactions and intramolecular catalysis.
• Bioorganic Mechanisms: The application of mechanistic organic chemistry to the mechanism of action of biological compounds. Emphasis may center on drug action or enzyme catalysis.
• Stereochemistry: Molecular configurations, conformations, and sterochemical effects in the organic reactions of carbon and heteroatom compounds.
• Reactive Intermediates: Organic chemistry of reactive intermediates such as carbenes, nitrenes and free radicals.