VOL. LIV, NO. 37
California State University, Long Beach November 3 , 2003
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. News  
 

CSULB herpes research aims to develop vaccine

By Mari Shinkai
Daily Forty-Niner

What is the disease, which affects more than 25 percent of women over the age of 12 in the United States? The answer is neither diabetes nor breast cancer, but herpes.

More than 25 percent of the U.S. population has genital herpes, possibly raising annual associated costs from $1.8 billion to $2.7 billion, according to the Washington Times.

Cal State Long Beach women ages 18 to 30 have the opportunity to participate in a research project to develop a vaccine against genital herpes, which may be one of the first vaccines available to prevent sexually transmitted diseases.

"Herpes is a lifelong infection that is caused by a virus and can be spread to those you love unknowingly," said Mike Carbuto, chief physician at Student Health Services and principal investigator for the campus research project.

The virus can travel the nerve pathways in a particular part of the body and hide away in the nerve roots for long periods of time, and genital herpes can cause painful physical lesions that often reoccur without warning.

The study will evaluate the safety and effectiveness of a vaccine to prevent genital herpes.

The earlier studies show that approximately 73 percent of women who were free of herpes simplex type 1 [HSV-1] and type 2 [HSV-2] infection at the beginning of the trials and who received the vaccine were protected against genital herpes.

Nationally, more than 20 sites are participating in the study and the three Los Angeles sites, Cal State Long Beach, Cal State Dominguez Hills and UCLA, expect to enroll between 400 to 500 eligible women.

Currently, a total of 28 women have been enrolled so far for the three Los Angeles sites, said Janet L. Baker, Herpevac clinical research nurse at Student Health Services.

"We are also looking for volunteers who want to be part of the major national study in the office here, particularly students from health sciences major," Baker said.

"If we can prove this vaccine to be beneficial, we will be able to wipe out the genital herpes issue within one or two generations. That's pretty powerful," Baker said.

The experimental herpes vaccine will not cause HSV infection and has met safety requirements needed for larger clinical trials.

For more information about the herpes vaccine trial, visit Web site: www.herpesvaccine.nih.gov. For participation information, call (562) 985-4874 or visit the Student Health Services.

 


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