CSULB science professors awarded research
grant
By Sarah LaVoie
Daily Forty-Niner
Two Cal State Long Beach professors were
among three Cal State University professors awarded a four-year grant for
$1.03 million to conduct a research project on the role of metals in biological
systems.
Professor Zed Mason of the department of
biological science and Roger Acey, professor of chemistry and biochemistry
will work with Cal State Los Angeles Professor Feimeng Zhou for four years.
Undergraduate science students at Cal State Long Beach will be assisting
professors in conducting the research.
The cutting-edge research project involves
the use of a newly developed technique that will allow them to analyze
tiny amounts of metal and look at their transfer from protein to protein.
"As far as I am aware, we are the only
group who has the technology to do this," Mason said.
The professors are trying to understand
the cells' ability to regulate concentrations of metals to maintain optimum
levels, neither too high nor too low.
If the concentration is too high cells
encounter toxicological problems and if the levels are too low, deficiency
becomes a problem, said Mason. Both can be possibly lethal.
"One of the problems is that although metals
are essential and you die without them," Mason said. "If you have too much
of them, you also die."
"Understanding metal metabolism and how
it's controlled is fundamentally important in biology," he said.
The professors will need at least eight
students to assist in conducting their research. This research
can be applied to everything from medicine to aquatic toxicology, pollution
studies and ecology, Mason said.
There are nonessential metals such as mercury,
cadmium, and lead, which are pollutants when released into the environment.
The researchers hope to discover the mechanisms by which these metals are
toxic and how they interact to cause toxicity.
This research may also assist in understanding
copper metabolism problems that cause syndromes such as Wilson's Disease
and Menke's Disease, and may assist in their treatment.
The result of this research can potentially
provide a basic understanding of cells and how they accumulate, store and
excrete metals in the human body. |