College of Natural Sciences and Mathematics
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Lab Personnel

Editte Gharakhanian, Ph.D Principal Investigator

Professor, Department of Biological Sciences, MLSC, Room 231

Contact: E.Ghara@csulb.edu

Editte Gharakhanian

Christopher Frost

Chris Frost

Lifetime Gharakhanian Lab Member.

B.S. Microbiology (CSULB, 2002), B.S. Biology (CSULB, 2002), M.S. Biochemistry (CSULB 2005)

Currently, Chris provides training to incoming lab members. He also assists with various laboratory operations including experiments involving yeast microscopy.

Surya Manandhar

Surya Manandhar

Post-Doctoral Research Associate

General Medicine from Institute of Medicine, Tribhuvan University, Kathmandu, Nepal; Ph.D. in Biochemistry from Kharkov State University, Kharkov, Ukraine (USSR); M.S. in Biochemistry from Kharkov State University, Kharkov, Ukraine (USSR).

Surya’s research is focused on understanding yeast ENV7p, product of a gene ENV7 that is not yet characterized, but apparently involved in sorting proteins at late endosome-to-vacuolar interface. Using molecular, biochemical and microscopic approaches, Surya intends to characterize this gene/protein in respect to its cellular localization and biological functions in Saccharomyces cerevisiae. 

Daniele Esquenazi Ejzykowicz

Daniele Esquenazi Ejzykowicz

Post-Doctoral Research Associate

Ph.D. in Cellular Biology, B.S. in Microbiology

Daniele is currently studying the Tor1 vacuolar membrane localization in Hygromycin B hypersensitive (hhy) mutants of Saccharomyces cerevisiae and its role on vesicular trafficking.

Ikha Mansoora

Ikha Mansoora

Graduate Research Assistant

Candidate for Master of Science degree in Biology, B.S. in Molecular, Cell & Developmental Biology

My project is further characterization of ENV9 gene product which we have confirmed to be localized to lipid droplets and may be a possible oxidoreductase enzyme conserved in humans. I am also studying a double mutant where both ENV9 and ENV10 genes are deleted, since the double deletion mutant suggests genetic interactions between the two genes.

Priscilla Bravo

Priscilla Bravo

Graduate Research Assistant

Candidate for Master of Science degree in Biology, B.S. in Biology

I am involved in categorizing the effects of hygromycin B on the TOR kinase signaling pathway in Saccharomyces cerevisiae. One of the roles of the TOR pathway in mammalian cells is regulation of cell growth and division; by observing the state of the TOR pathway in hhy mutants and in presence of hygromycin B, we can learn more about how TOR kinase activity can be controlled at the molecular level. Such information may be relevant to diseases associated with upregulation of TOR in humans, such as cancer and diabetes.

Erika Calle

Erika Calle

Undergraduate Research Assistant

I am currently working on further characterization of Env7p function in regulation of vacuole fusion by confocal microscopy.

Fiona Ruiz

Fiona Ruiz

Undergraduate Research Assistant

I am currently working with a group of vesicular trafficking genes called the super hypersensitive to hygromycin genes (s-hhy). My project is to determine whether these mutant strains can undergo autophagy, a defense mechanism cells use when under starvation and stress.

Raffi Melikian

Undergraduate Research Assistant

Raffi Melikian

I am currently studying the env9/10 and env11/vid22 double deletion mutants, and characterizing their defects in vacuolar and fitness events.

Don Ha

Don Ha

Undergraduate Research Assistant

I am assisting Ikha to characterize the growth patterns, lipid droplet morphology, and vacuolar morphology of env9/10Δ double mutant.This characterization process is examined in the context of lipid stress under partial and complete glucose deprivation

Bryan Dighera

High School Intern

Past Lab Members

Teli Hsueh

Teli Hsueh

Graduate Research Assistant

Maribeth Serranilla

Maribeth Serranilla

Graduate Research Assistant

Lisa Olivera

Lisa Olivera

Graduate Research Assistant

Stephanie Cocca

Stephi Cocca

Graduate Research Assistant

Kristopher Locken

Kristopher Locken in the lab

Graduate Research Assistant

Julie Smithwick

Julie Smithwick

Undergraduate Research Assistant

Florante Ricarte

Florante Ricarte

Tattika Soreta

Undergraduate Research Assistant