A researcher must have a broad knowledge of animal physiology and organic chemistry to determine what would be the best animal model and procedure for the given research. Fortunately there are "search programs" which assist the researcher in finding the latest information about Alternatives. You will find a procedures alternative search engine in the "Science and Regulation" section of the "Alternatives to Testing" website. References are there also for MEDPUB and TOXLINE.
Other methods for responding to the imperatives of "replacement," "reduction," and "refinement" are: MEDLINE under the National Library of Medicine, AGRICOLA and other services at the National Agricultural Library, Biological Abstracts, CRISP, Biological Cybernetics, professional journals, professional meetings, and last but definitely not least, personal communications with colleagues. Check the "Resources" below for the websites.