Using this form
This form is adapted from the OLAW model continuation report
form at http://grants.nih.gov/grants/olaw/references/contop96.htm
Section 1 "Summary of Animal Use"
is completed by the Office of University Research, except
for numbers of animals caught in the wild and the "Remainder"
(in Part A.), and wild-caught released, expended, or still housed in the facility (in Part
B.)
"Remainder" is equal to the Total Approved (or the previous
year's Remainder) minus the number purchased, caught, or transferred
in.
When authorized by the IACUC for multiple-species protocols,
such as fish trawls, for example, the exact species/strain
will not be listed, and instead only the combined total of
all species.
Section 2 is completed
by the PI.
Section 3 is completed
during the review by the IACUC.
Section 4 is completed
by the PI.
Section 5 is completed
by the PI.
Section 6 is completed
by the PI.
Section 7--Progress
Report is completed by the PI. The progress in achieving the
specific aims of the protocol should be described, including
a brief summarization of the biomethodology involved (what
exactly happens to the animals). The information in this section
should be provided as an update to help the IACUC document the
continued approvability of the research. For example, if 50
mice were used and the investigator had no progress to report,
in light of the specific aims of the protocol, it would be
reasonable for the IACUC to request clarification. It should,
however, be recognized that scientific inquiry may involve
"blind alleys", and failed experiments, thus resulting in
little progress in the short- versus long-term.
Section 8--Problems/Adverse
Events is completed by the PI. Any unanticipated problems
or adverse events that have occurred should be reported at
the time of the problem or event and summarized here in the
Annual Report, including an explanation of how these events/problems
were resolved. Depending on the information provided here,
this response may also need to be factored into the IACUC's
assessment of the ethical cost-benefit justification.
Section 9--Search
for Alternatives: Replacement, Refinement, and Reduction is completed by the PI. Answer Replacement
each year; answer Refinement each year if USDA Category D
or E; answer Reduction each year.
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Prior to submission,
the investigator is requested to share the completed Annual
Report with the Attending Veterinarian, John
Young, by attaching it to an email. Please note that this
step may consume extra days prior to the IACUC agenda deadline.
Finally, the investigator
is asked to sign the Annual Report Form, which contains
a certification of his/her understanding and responsibility
for conduct of animal activities in accordance with the PHS
Policy, USDA regulations and the institution's IACUC policies.
Signature here also attests to the accuracy of the investigator's
responses. Requiring completion of this form, at every anniversary
of the project (including the last), indicates to the investigator
the seriousness of the IACUC's review and the importance of
investigator accountability for his/her research activity;
for reporting it accurately; and for justifying continuance
of the research project for another year (or for the disposition
of remaining animals if the project is ending). Accordingly,
the IACUC, through its designated reviewer mechanism (when implemented
for summer or winter periods by vote of the IACUC), is also
held accountable for appropriate and responsible review of
the IACUC protocol file, and for continuation approval of ongoing
animal research, if it is still justified.
This method of
IACUC continuing review.
At each review of
an Annual Report all IACUC members will have available at the
Committee meeting the original approved protocol.
A complete new
IACUC protocol application form must be submitted if a project will
extend beyond three years.
In summary, the review process and
report form described meet the requirements of the PHS Policy
and the USDA regulations for continuing review. |
