The majority of the PDF files on the web are probably created in Microsoft Word. The good news is that it is possible to create accessible PDF files in Microsoft Office, as long as the following requirements are met:
Once Word document is formatted , choose "Adobe "PDF" and "Preferences"
On "Settings" tab, check Bookmarks, Links, and Enable Accessibility and Reflow. Not available in Acrobat 07: Fully Functional and Quick and Simple PDF.
On the "Security" tab, if Permissions are applied, check enable text accessfor screen reader devices for the visually impaired.
On "Word" tab, check Convert cross-refences, Convert footnote, and Enable advanced tagging.
On "Bookmarks" tab, check Convert Word Headings ... and set indent levels.
Now save your document as an accessible PDF.